New Isn’t Everything

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The ISNT rule and differentiation of normal from glaucomatous eyes.

OBJECTIVE To determine whether the ISNT rule (that normal eyes show a characteristic configuration for disc rim thickness of inferior > or = superior > or = nasal > or = temporal), widely used for clinical evaluation of the optic nerve head, can differentiate normal from glaucomatous eyes. METHODS All subjects underwent complete eye examination, including achromatic automated perimetry, simul...

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Factors Affecting ISNT Rule Satisfaction in Normal and Glaucomatous Eyes

PURPOSE To determine the factors that influence the satisfaction of the 'ISNT rule' (neural rim width: inferior ≥ superior ≥ nasal ≥ temporal) in normal and glaucomatous eyes. METHODS The medical records of patients that visited Boramae Medical Center, Seoul, Korea, were reviewed. Each group of normal and glaucomatous eyes was divided into subgroups based on whether or not they satisfied the ...

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Post-influenza pneumonia: everything old is new again.

MEDICINE & HEALTH/RHODE ISLAND The 1918-1919 Influenza pandemic spread worldwide with remarkable speed. Approximately 500 million people were infected, and the death toll was between 50 and 100 million worldwide. It is hypothesized that a major cause of morbidity and mortality may not have been the viral pneumonitis, but the bacterial superinfection of the susceptible postinfluenza lung. Here, ...

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Everything old is new again: (linc)RNAs make proteins!

Long non-coding RNAs have become the focus of considerable interest over the past few years. Intriguing novel functions have been reported for lincRNAs. Three recent papers identify lincRNAs that work in a more conventional way-encoding protein-in each case a small polypeptide with an interesting biological activity (Magny et al, 2013; Pauli et al, 2014), (Bazzini et al, 2014).

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ژورنال

عنوان ژورنال: Cell Systems

سال: 2017

ISSN: 2405-4712

DOI: 10.1016/j.cels.2017.07.001